More than 50% risk reduction of VAP with Bactiguard’s Technology
A new Belgian study published in the renowned journal Annals of Intensive Care, shows that the risk of VAP in intensive care patients is reduced by 53% when using Bactiguard’s endotracheal tubes with subglottic secretion drainage (BIP ETT Evac).1
Even a short treatment with endotracheal tubes, can make the patient develop ventilator associated pneumonia (VAP), a very serious respiratory tract infection that can affect intubated patients. VAP is the second most common healthcare associated infection in the ICU,2-4 and microbial adhesion on the tube resulting in biofilm formation is a contributing factor to infection.
Reduces microbial adhesion on the tube
The Bactiguard technology (Bactiguard Infection Protection) is based on a very thin noble metal alloy coating, firmly attached to the catheter surface. When in contact with fluids, the noble metals create a galvanic effect which reduces microbial adhesion. This means that less bacteria adhere to the tube surface, which reduces the risk of biofilm formation leading to infection.
Subglottic secretion drainage further reduces the risk of infection
BIP ETT Evac is the only tube on the market that combines the subglottic secretion drainage with the ability of the Bactiguard coating to reduce microbial adhesion. Meta-analysis of randomized, controlled studies have consequently shown reduction of VAP with approximately 50% when using tubes with subglottic secretion drainage.5
Safe to use
The technology is safe to use, the coating is firmly attached to the tube and the amount of noble metals at the surface is very low and below all safety limits for each metal. There is no release of any toxic or pharmacological quantities, as opposed to traditional coating technologies that often depend on the release of substances that kill bacteria, e.g. high concentrations of silver ions, chlorhexidine or antibiotics.
The technology is well proven, more than 100,000 patients have been included in clinical trials and over 200 million products have been used without any reported side adverse events related to the coating.
The BIP ETT Evac is used to secure an open airway during anesthesia or when intubation is necessary as part of standard medical care. It is inserted through the mouth into the trachea and connected to a ventilator.
Bactiguard’s endotracheal tube is available with or without subglottic secretion drainage; BIP ETT Evac and BIP ETT. The beveled tip, Murphy Eye and high volume-low pressure cuff are designed to minimize the risk of damages to the patients’ trachea and ensure safe usage.
BIP ETT Evac is made of phthalate-free PVC and coated with the Bactiguard coating on both the inside and outside of the tube. It is approved for use for up to 30 days.
References: 1. Damas, P., Legrain, C., Lambermont, B. et al. Prevention of ventilator-associated pneumonia by noble metal coating of endotracheal tubes: a multi-center, randomized, double-blind study. Ann. Intensive Care12, 1 (2022). https://doi.org/10.1186/s13613-021-00961-y 2. Craven DE et al. Infect. 1996;11(1):32-53. 3. Rello J et al. Chest. 2002;122(6):2115-2121. 4. Kollef MH et al. Chest. 2005; 128 (6):3854-3862. 5. Haas CF et al. Respir Care. 2014; Jun; 59(6):933-52.